when you have to adminster antibiotic for Pyuria

There is no need to treat pus cells in urine (pyuria), even if the count exceeds 100, as long as there are no noticeable symptoms. In the absence of symptoms, a urine culture or treatment is unnecessary except in the following three specific cases:

  1. If you have undergone a kidney transplant: Because the weakened immune system in this situation makes treating any infection crucial.
  2. If you are pregnant: Untreated infections could pose risks to both the mother and the baby.
  3. If you are scheduled to undergo a medical procedure or surgery involving the kidneys: To ensure the prevention of any potential complications.

Outside of these cases, there is no need for treatment or medical intervention if the individual is asymptomatic.

Additional Info:

  • This approach aligns with modern guidelines for managing asymptomatic bacteriuria or pyuria, which emphasize avoiding unnecessary antibiotic use to prevent resistance.
  • Routine testing in asymptomatic individuals is generally discouraged unless risk factors like pregnancy or immunosuppression are present.
  • If symptoms do develop, such as pain, fever, or urinary discomfort, further investigation and treatment may be required.


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