Detection of pathogens and parasites ova in complete stool analysis has a limited role now in world advanced countries as emerging stool PCR has been listed as standard clinical examination
Stool PCR (polymerase chain reaction) has indeed revolutionized the detection and diagnosis of gastrointestinal infections. By amplifying and detecting the DNA or RNA of pathogens directly from stool samples, it allows for rapid and highly accurate identification of a variety of infectious agents, including bacteria, viruses, and parasites. This precision reduces the need for prolonged culture-based methods, which are often time-consuming and less sensitive, especially for certain hard-to-culture pathogens.
Moreover, stool PCR’s quick turnaround times significantly enhance clinical decision-making, enabling prompt treatment that can improve patient outcomes and help limit the spread of infections. In research, stool PCR also facilitates epidemiological studies by providing a reliable method for tracking and analyzing the prevalence and diversity of pathogens in populations.
As molecular diagnostic technology continues to evolve, stool PCR is expected to become even more refined, potentially with expanded multiplex panels that can detect multiple pathogens simultaneously. This advancement will be critical for improving the diagnosis, management, and understanding of complex gastrointestinal infections and for enhancing public health responses to outbreaks.
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